| Missplicing of a brain-specific exon of Bin1 in human melanoma is sufficient to abolish tumor suppressor properties; ectopic WT Bin1 activates PCD in malignant but not normal melanocytes. | skin,brain, |
| Losses of the tumor suppressor BIN1 in breast carcinoma are frequent and reflect deficits in programmed cell death capacity. | breast, |
| Loss of heterozygosity and tumor suppressor activity of Bin1 in prostate carcinoma. | prostate, |
| Loss of the IDO regulatory tumor suppressor gene Bin1 in transformed skin cells facilitates IDO-mediated immune escape. | skin, |
| The c-MYC-interacting proapoptotic tumor suppressor BIN1 is a transcriptional target for E2F1 in response to DNA damage. | None |
| study characterized interaction of NS5A with SH3 domains of several kinases and tumor suppressor Bin1; these binding regions partially overlap with regions that have previously been identified as having an increased propensity to form alpha-helices | None |
| Basal PARP1 activity was sufficient to modify E2F1 by poly(ADP-ribosyl)ation, which stabilized the interaction between E2F1 and the BIN1 tumor suppressor in the nucleus | None |
| Methylation decreases the Bin1 tumor suppressor in ESCC and restoration by decitabine inhibits the epithelial mesenchymal transition | None |
| Loss of the tumor suppressor BIN1 enables ATM Ser/Thr kinase activation by the nuclear protein E2F1 and renders cancer cells resistant to cisplatin | None |
| A nucleocytosolic myc-interacting isoform of Bin1 has properties of a tumor suppressor. | None |
| A role for the putative tumor suppressor Bin1 in muscle cell differentiation. | None |