| The present immunohistochemical study confirmed 14-3-3sigma as a tumor suppressor in breast carcinogenesis. | breast, |
| Loss of 14-3-3-sigma sensitizes mice to chemically-induced skin carcinogenesis. Therefore, 14-3-3-sigma may indeed represent a mediator of tumor suppression in the skin. | skin, |
| Stratifin was first identified as an epithelial cell antigen exclusively expressed in epithelia. the functional role of sfn in cell proliferation and apoptosis could be relevant to the regulation of growth and differentiation as a tumor suppressor gene | None |
| this study identified the p53 regulated tumor suppressor 14-3-3sigma as a direct plakoglobin-p53 target gene. | None |
| These results suggest that SFN facilitates lung tumor development and progression. SFN appears to be a novel oncogene with potential as a therapeutic target | lung, |