| data provide evidence for a tumour suppressor role of Trib2 in myeloid leukaemia via activation of p38 stress signalling. This newly identified role indicates that Trib2 may counteract the propagation and chemotherapy resistance of leukaemia cells. | None |
| Data identify Tribbles homolog 2 as an oncogene that induces acute myelogenous leukemia through a mechanism involving inactivation of C/EBPalpha. | leukemia, |
| High TRIB2 reinforces the oncogenic transcriptional program controlled by the TAL1 complex in T-cell acute lymphoblastic leukemia. | leukemia, |
| TRIB2 reinforces the oncogenic transcriptional program controlled by the TAL1 complex in T-cell acute lymphoblastic leukemia. | leukemia, |
| Tribbles breaking bad: TRIB2 suppresses FOXO and acts as an oncogenic protein in melanoma. | skin, |
| miR-206 and miR-140, as tumor suppressors, induced lung adenocarcinoma cell death and inhibited cell proliferation by modifying oncogenic TRIB2 promoter activity through p-Smad3. | lung, |
| Let-7c inhibits A549 cell proliferation through oncogenic TRIB2 related factors. | None |
| Results identify trbl as a direct bantam target gene that mediates its growth regulatory role and oncogenic function. trbl downregulation in the wing disc accelerates G2/M progression in the cell cycle. | None |