| Transcriptional silencing of the TMS1/ASC tumour suppressor gene by an epigenetic mechanism in hepatocellular carcinoma cells. | liver, |
| ASC/TMS1 methylation was significantly correlated with higher tumor nuclear grade. ASC/TMS1 is a novel functional tumor suppressor in renal carcinogenesis. | kidney, |
| A tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4. | None |
| Our data identify RIPK3 and the ASC inflammasome as key tumor suppressors in AML. | None |
| ASC may be involved in tumor suppression and cell death via Bcl-2 and phosphor Src. | None |