| These results suggested that BRD7 acts as a tumor suppressor in epithelial ovarian cancers | ovarian, |
| our data indicated that BRD7 may serve as a tumor suppressor in hepatocellular carcinoma | liver, |
| Overexpression of BRD7 inhibited cyclin D and myc expression. Our findings are consistent with a tumor suppressor role for BRD7 in lung adenocarcinoma tumorigenesis. | lung, |
| BRD7 is a candidate tumour suppressor gene required for p53 function. | None |
| Here we further discuss the role of BRD7 as a cofactor in transcriptional regulation and highlight its role as a tumor suppressor via association with p53 and other tumor suppressor proteins. | None |
| the expression of miR-141 in BRD7-overexpressing NPC cells could partially reverse the tumor suppressive effect of BRD7 on cell proliferation and tumor growth in vitro and in vivo. | None |
| BRD7: a novel tumor suppressor gene in different cancers | None |
| Results demonstrate a novel function of BRD7 in TGF-beta signaling. BRD7 interacts with the Smad tumor suppressor complex, and enhances both DNA-binding ability and transcriptional activity of Smads. BRD7 functions in growth inhibition and tumor suppression partly as a transcriptional co-activator of Smads. | None |