| The expression of GLTSCR2, a candidate tumor suppressor, is reduced in seborrheic keratosis compared to normal skin. | skin, |
| Regulation of PTEN phosphorylation and stability by a tumor suppressor candidate protein. | None |
| Critical role of PICT-1, a tumor suppressor candidate, in phosphatidylinositol 3,4,5-trisphosphate signals and tumorigenic transformation. | None |
| The putative tumor suppressor gene GLTSCR2 induces PTEN-modulated cell death. | None |
| results suggest that the induction of PTEN-modulated apoptosis is one of the putative mechanisms of tumor suppressive activity by GLTSCR2 | None |
| study describes a novel interaction between KS-Bcl-2 & PICT-1 cellular protein, encoded by a candidate tumor suppressor gene, GLTSCR2; show this interaction specifically targets KS-Bcl-2 to the nucleolus & decreases its antiapoptotic activity | None |
| GLTSCR2 seems to act as a tumor suppressor by participating in optimal DNA damage response because DNA damage is a frequent and crucial event in oncogenesis. | None |
| GLTSCR2 functions as a tumor suppressor in prostatic adenocarcinomas. | None |
| Study reports the identification of adaptor proteins that recruit the exosome-associated helicase, Mtr4, to unique RNA substrates. Nop53, the yeast homolog of the tumor suppressor PICT1, targets Mtr4 to pre-ribosomal particles for exosome-mediated processing, while a second adaptor Utp18 recruits Mtr4 to cleaved rRNA fragments destined for degradation by the exosome. | None |