Sentence and cancer type
Showing 1-20 of 23 items.
SentenceCancertype
Detailed mapping of chromosome 17p deletions reveals HIC1 as a novel tumor suppressor gene candidate telomeric to TP53 in diffuse large B-cell lymphomalymphoma,
Data report that novel tumor suppressor HIC1 is required for growth suppression by estrogen antagonists in breast cancer cells.breast,
A potential tumor suppressor role for Hic1 in breast cancer through transcriptional repression of ephrin-A1.breast,
Promoter hypermethylation of RASSF1A, MGMT, and HIC-1 genes in benign and malignant colorectal tumors.colorectal,
Identification of novel subregions of LOH in gastric cancer and analysis of the HIC1 and TOB1 tumor suppressor genes in these subregions.gastric,
Alterations in Promoter Methylation Status of Tumor Suppressor HIC1, SFRP2, and DAPK1 Genes in Prostate Carcinomas.prostate,
Methylation of the Tumor Suppressor Genes HIC1 and RassF1A Clusters Independently From the Methylation of Polycomb Target Genes in Colon Cancercolorectal,
KRAS, BRAF oncogene mutations and tissue specific promoter hypermethylation of tumor suppressor SFRP2, DAPK1, MGMT, HIC1 and p16 genes in colorectal cancer patientscolorectal,
IL-6 present in the tumor microenvironment downregulates the tumor suppressor HIC1 in breast cancer cells.breast,
Methylation of the HIC-1 candidate tumor suppressor gene in human breast cancer.breast,
Mice deficient in the candidate tumor suppressor gene Hic1 exhibit developmental defects of structures affected in the Miller-Dieker syndrome.None
Characterization of HRG22, a human homologue of the putative tumor suppressor gene HIC1.None
The human candidate tumor suppressor gene HIC1 recruits CtBP through a degenerate GLDLSKK motif.None
Identification of a second G-C-rich promoter conserved in the human, murine and rat tumor suppressor genes HIC1.None
The tumor suppressor gene HIC1 (hypermethylated in cancer 1) is a sequence-specific transcriptional repressor: definition of its consensus binding sequence and analysis of its DNA binding and repressive properties.None
HIC1 is involved in a certain feedback regulation for p53 in tumor suppression through histone deacetylase. (review)None
An acetylation/deacetylation-SUMOylation switch through a phylogenetically conserved psiKXEP motif in the tumor suppressor HIC1 regulates transcriptional repression activity.None
The tumor suppressor gene hypermethylated in cancer 1 is transcriptionally regulated by E2F1.None
The tumor suppressor HIC1 is implicated in the transcriptional regulation of the chemokine receptor CXCR7, a key player in the promotion of tumorigenesis in a wide variety of cell types.None
Generation of two modified mouse alleles of the Hic1 tumor suppressor gene.None