Sentence and cancer type
Showing 21-40 of 80 items.
SentenceCancertype
Apoptosis in neural crest cells by functional loss of APC tumor suppressor gene.None
The coiled coil region (amino acids 129-250) of the tumor suppressor protein adenomatous polyposis coli (APC). Its structure and its interaction with chromosome maintenance region 1 (Crm-1).None
Structure of the amino-terminal nuclear export domain of the APC tumor suppressor protein.None
Requirement for tumor suppressor Apc in the morphogenesis of anterior and ventral mouse embryo.None
The tumor suppressor adenomatous polyposis coli and caudal related homeodomain protein regulate expression of retinol dehydrogenase L.None
Isoforms of the APC tumor suppressor and their ability to inhibit cell growth and tumorigenicity.None
The APC tumor suppressor binds to C-terminal binding protein to divert nuclear beta-catenin from TCF.None
Tumor suppressor APC blocks DNA polymerase beta-dependent strand displacement synthesis during long patch but not short patch base excision repair and increases sensitivity to methylmethane sulfonate.None
Subcellular localization of the tumor suppressor protein APC in developing cultured neurons.None
APC induces apoptosis and thus plays a role in tumor suppression.None
The APC tumor suppressor promotes transcription-independent apoptosis in vitro.None
The tumor suppressor adenomatous polyposis coli gene is associated with susceptibility to schizophrenia.None
This gene encodes a tumor suppressor protein that includes among its many intracellular functions one of nuclear export. Defects in this gene cause familial adenomatous polyposis (FAP).None
The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes.None
Human scribble, a novel tumor suppressor identified as a target of high-risk HPV E6 for ubiquitin-mediated degradation, interacts with adenomatous polyposis coli.None
The adenomatous polyposis coli tumor suppressor gene regulates expression of cyclooxygenase-2 by a mechanism that involves retinoic acid.None
genomic instability is an early event that occurs at precancerous stages prior to changes in tumor suppressor genes (p53 and APC) in Barrett_s esophagus-associated tumorigenesis in patientsNone
Characterization of a 60S complex of the adenomatous polyposis coli tumor suppressor protein.None
Caspase cleavage of the APC tumor suppressor and release of an amino-terminal domain is required for the transcription-independent function of APC in apoptosis.None
Familial adenomas polyp is caused by mutations in the APC tumor suppressor gene.None