| The APC tumor suppressor mutation was ssessed in the ability of apigenin in induce cell cycle arrest in HT29-APC cells. | None |
| The APC tumor suppressor inhibits DNA replication by directly binding to DNA via its carboxyl terminus. | None |
| The armadillo repeat domain of the APC tumor suppressor protein interacts with Striatin family members. | None |
| Interaction between tumor suppressor adenomatous polyposis coli and topoisomerase IIalpha: implication for the G2/M transition. | None |
| The SCF(beta-TrCP) binding site created by phosphorylation of beta-catenin is highly vulnerable to protein phosphatase 2A (PP2A) and must be protected by the adenomatous polyposis coli (APC) tumor suppressor protein. | None |
| A missense mutation in the APC tumor suppressor gene disrupts an ASF/SF2 splicing enhancer motif and causes pathogenic skipping of exon 14. | None |
| Atonal homolog 1 is a tumor suppressor gene. | None |
| The APC tumor suppressor is required for epithelial integrity in the mouse mammary gland. | None |
| These results suggest that APC expression is tightly regulated during mammary gland development and is required for normal mammary homeostasis and tumor suppression primarily through maintaining epithelial integrity. | None |
| A targeted constitutive mutation in the APC tumor suppressor gene underlies mammary but not intestinal tumorigenesis. | None |
| The receptor tyrosine kinase EPHB4 has tumor suppressor activities in intestinal tumorigenesis. | None |
| The mitochondrial protein hTID-1 partners with the caspase-cleaved adenomatous polyposis cell tumor suppressor to facilitate apoptosis. | None |
| The adenomatous polyposis coli tumor suppressor and Wnt signaling in the regulation of apoptosis. | None |
| Recql5 has a tumor suppressor role in the gastrointestinal tract of Apc(min) mice. | None |
| F-box and WD repeat domain-containing 7 regulates intestinal cell lineage commitment and is a haploinsufficient tumor suppressor. | None |
| Hepatitis B viral X protein interacts with tumor suppressor adenomatous polyposis coli to activate Wnt/??-catenin signaling. | None |
| Data suggest that localised regulation of APC-phospho-beta-catenin complexes may contribute to the tumour suppressor activity of APC. | None |
| Messing up disorder: how do missense mutations in the tumor suppressor protein APC lead to cancer? | None |
| Several mechanisms by which cancer-related missense mutations in the large disordered domain of APC may interfere with tumor suppressor activity. | None |
| The tumor suppressor adenomatous polyposis coli controls the direction in which a cell extrudes from an epithelium. | None |