| the tumor suppressor adenomatous polyposis coli controls microtubule targeting to the cell base to drive apical extrusion during cell death | None |
| Adenomatous polyposis is caused by autosomal dominantly inherited mutations in the APC (Adenomatous polyposis coli) gene, a tumour suppressor gene that controls beta-catenin turnover in the Wnt pathway. | None |
| Data suggest that hDlg may serve as a platform to bring in proximity APC and PTEN tumor suppressor activities. | None |
| A discrete trimeric complex of beta-catenin, alpha-catenin and the tumor suppressor APC, forms in the cytoplasm in response to Wnt signaling. | None |
| tumor suppressor Apc controls planar cell polarities central to gut homeostasis | None |
| the C-terminus of the Apc tumor suppressor plays a critical role in cognitive and neuropsychiatric functioning. | None |
| Wnt/Wingless Pathway Activation Is Promoted by a Critical Threshold of Axin Maintained by the Tumor Suppressor APC and the ADP-Ribose Polymerase Tankyrase | None |
| Intestinal stem cell overproliferation resulting from inactivation of the APC tumor suppressor requires the transcription cofactors Earthbound and Erect wing | None |
| Functions of the APC tumor suppressor protein dependent and independent of canonical WNT signaling: implications for therapeutic targeting | None |
| Tumor suppressor APC is an attenuator of spindle-pulling forces during C. elegans asymmetric cell division | None |
| Axin phosphorylation in both Wnt-off and Wnt-on states requires the tumor suppressor APC | None |
| End-binding proteins (EBs), referred to as the core components of the microtubule plus-end tracking protein network, interact with the C-terminus of the adenomatous polyposis coli (APC) tumor suppressor. APC is a promoter of EB interaction with microtubules. | None |
| Association of plakoglobin with APC, a tumor suppressor gene product, and its regulation by tyrosine phosphorylation. | None |
| Association of the APC tumor suppressor protein with catenins. | None |
| Binding of APC to the human homolog of the Drosophila discs large tumor suppressor protein. | None |
| Tumor suppressor gene mutations in mice. | None |
| A Drosophila homolog of the tumor suppressor gene adenomatous polyposis coli down-regulates beta-catenin but its zygotic expression is not essential for the regulation of Armadillo. | None |
| Cloning and characterization of NE-dlg: a novel human homolog of the Drosophila discs large (dlg) tumor suppressor protein interacts with the APC protein. | None |
| Binding of high-risk human papillomavirus E6 oncoproteins to the human homologue of the Drosophila discs large tumor suppressor protein. | None |
| Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta. | None |