Sentence and cancer type
Showing 421-440 of 559 items.
SentenceCancertype
Impact of SNPs on CpG Islands in the MYC and HRAS oncogenes and in a wide variety of tumor suppressor genes has been analyzed in a multi-cancer bioinformatics approach.None
Together, these results suggest a novel mechanism regulating PATZ1 expression based on the upregulation of miR-29b expression induced by Ras oncogene.None
these contrasting signatures precisely match those proposed to confer bias toward Hras(CAA61CTA) versus Braf(GTG636GAG) mutations in the original tumor sets. Our findings highlight a novel mechanism whereby exposure history acts through strand-biased mutagenesis to specify activation of preferred oncogenesNone
ESR1 inhibits senescence-like phenotype and facilitates transformation induced by oncogenic ras in human mammary epithelial cellsNone
we found that ectopic expression of oncogenic KRas and HRas in cells resulted in elevated CIB1 expression. We previously described the Ca(2+)-myristoyl switch function of CIB1, and its ability to facilitate agonist-induced plasma membrane localisation of sphingosine kinase 1 (SK1), a location where SK1 is known to elicit oncogenic signalling.None
Studies indicate that RAS proteins were among the first oncogenes identified and are mutationally activated in 30% of all cancer types.None
Studies on the promoter region of the c-Ha-ras oncogene. None
Co-operation in cell transformation between BK virus and the human c-Harvey-ras oncogene. None
Cooperation in oncogenesis between BK virus early region gene and the activated human c-Harvey ras oncogene. None
Cotransfection of granulosa cells with simian virus 40 and Ha-RAS oncogene generates stable lines capable of induced steroidogenesis. None
Different biological effects of c-myc and H-ras oncogene expression in EBV-infected human lymphoblasts. None
Transformation of BALB/3T3 cells with EJ/T24/H-ras oncogene inhibits adenylate cyclase response to beta-adrenergic agonist while increases muscarinic receptor dependent hydrolysis of inositol lipids. None
Detection of two TaqI polymorphisms in the VTR region of the human HRAS1 oncogene. None
Mechanism of H-ras oncogene activation in mouse squamous carcinoma induced by an alkylating agent. None
the oncogenic Hras mutation modulates energy homeostasis in vivo.None
PRKD1-mediated classical protein secretory pathway regulates the H-Ras oncogene-induced senescence-associated secretory phenotype.None
Tipifarnib effectively inhibits oncogenic HRAS-driven tumorigenesis and abrogating adaptive signaling improves responses. NF1 and GNAS mutations drive acquired resistance to Hras inhibition, supporting the on-target effects of the drugNone
Localization of the oncogene c-Ha-ras1 outside the aniridia-Wilms tumor-associated deletion of chromosome 11(del 11p13) using somatic cell hybrids. None
The immediate-early enhancer element of herpes simplex virus type 1 can replace a regulatory region of the c-Ha-ras1 oncogene required for transformation. None
Transformation of established murine fibroblasts with an activated cellular Harvey-ras oncogene or the polyoma virus middle T gene increases cell permissiveness to parvovirus minute-virus-of-mice. None