| conclusion: decreased IGFBP-4 tumor expression might be a step in the progression from primary to metastatic melanoma; data lend support to a recently-described novel tumor suppressor role of secreting IGFBPs in melanoma | skin, |
| Loss of tumor suppressor IGFBP4 drives epigenetic reprogramming in hepatic carcinogenesis | liver, |
| these findings demonstrate an oncogenic property for IBP in promoting the metastatic potential of breast cancer cells. | breast, |