| In prostate cancer cells, one of the downstream mediators of the senescence-associated tumor suppression effect of mac25/IGFBP-rP1 is superoxide dismutase 2 | prostate, |
| IGFBP7 plays a potential tumor suppressor role against colorectal carcinogenesis and its expression is associated with DNA hypomethylation of exon 1. | colorectal, |
| IGFBP7 plays a potential tumor suppressor role in colorectal carcinogenesis. | colorectal, |
| This study supports the role of IGFBP-1, -3 and -7 as potential tumour suppressor genes in human breast cancer. | breast, |
| Findings provide evidence that IGFBP7 functions as a novel putative tumor suppressor for HCC and establish the corollary that IGFBP7 downregulation can effectively modify AEG-1 function. | liver, |
| Insulin-like growth factor-binding protein-7 functions as a potential tumor suppressor in hepatocellular carcinoma. | liver, |
| These findings suggest a novel molecular mechanism responsible for the tumor suppressive function of IGFBP7 in cisplatin-resistant human lung cancer. | lung, |
| IGFBP-rP1 acts as a potential tumor suppressor via the suppression of ERK signaling pathway in endometrial cancer cells | endometrial, |
| A secreted tumor-suppressor, mac25, with activin-binding activity. | None |
| Similar to oncogenic BRAF-positive common naevi without atypia, enhanced expression of the tumour suppressor IGFBP7 in oncogenic BRAF-positive atypical genital nevi supports that they are biologically inert. | None |