| IRF5 is critical for antiviral immunity and for the induction of apoptosis, but not cell cycle arrest in response to DNA damage, and acts as a tumor suppressor on a pathway that may be distinct from that for p53. | None |
| IRF5 is an important tumor suppressor that regulates multiple cellular processes involved in the conversion of normal mammary epithelial cells to tumor epithelial cells with metastatic potential. | None |
| oncogenic IRF5 overexpression in HL is the result of a specific LTR transcriptional activation | None |