| Tumor-suppressive function of long noncoding RNA MALAT1 in glioma cells by downregulation of MMP2 and inactivation of ERK/MAPK signaling | glioma, |
| MALAT1 may function both as an oncogene and as a tumor suppressor in different types of thyroid tumors. | thyroid, |
| Tumor-suppressive function of long noncoding RNA MALAT1 in glioma cells by suppressing miR-155 expression and activating FBXW7 function | glioma, |
| we establish and characterize a non-canonical PTEN-microRNA-MALAT1 axis that regulates tumorigenesis and describe for the first time that the MALAT1 lncRNA possesses novel tumor suppressive properties in colon and breast cancers.#This is the parental gene. | None |
| The Oncogenic and Tumor Suppressive Functions of the Long Noncoding RNA MALAT1: An Emerging Controversy | None |
| MALAT1 might serve as an oncogenic lncRNA that promotes proliferation and metastasis of gallbladder cancer and activates the ERK/MAPK pathway. | bladder, |
| MALAT-1 may serve as an oncogenic lncRNA that is involved in malignancy phenotypes of pancreatic cancer. | pancreatic, |
| Up-regulation of long noncoding RNA MALAT1 contributes to proliferation and metastasis in esophageal squamous cell carcinoma. | esophageal, |
| oncogenic role in osteosarcoma | osteosarcoma, |
| Data suggest that MALAT1 could function as an oncogene in gastric cancer, and high MALAT1 level could serve as a potential biomarker for the distant metastasis of gastric cancer. | gastric, |
| MALAT1 may function both as an oncogene and as a tumor suppressor in different types of thyroid tumors. | thyroid, |
| data indicated that MALAT1 might play an oncogenic role in hilar cholangiocarcinoma (HCCA) through miR-204-dependent CXCR4 regulation, and could be regarded as a therapeutic target in HCCA. | liver,cholangiocarcinoma, |
| Our data revealed that MALAT1 inhibited tongue cancer cell growth and metastasis through miR-124-dependent JAG1 regulation. In conclusion, we revealed that MALAT1 may play an oncogenic role by increasing proliferation and metastasis of tongue cancer and is a potential therapeutic target in human tongue cancer. | tongue, |
| our work illuminates that lncRNA MALAT1 is a potential diagnostic and prognostic factor in osteosarcoma and further demonstrates how MALAT1 confers an oncogenic function. | osteosarcoma, |
| correlates with increased levels of Nischarin and inhibits oncogenic cell functions in breast cancer | breast, |
| Study finding suggests that MALAT1 may exert oncogenic function in papillary thyroid cancer and may be a potential diagnostic marker for this cancer. | thyroid, |
| The histone demethylase JMJD1A induces cell migration and invasion by up-regulating the expression of the long noncoding RNA MALAT1. | None |
| MALAT1 serves as an oncogene in ESCC, and it regulates ESCC growth by modifying the ATM-CHK2 pathway. | None |
| we have identified an oncogenic MALAT1-GLI1 fusion gene in all cases of gastroblastoma that may serve as a diagnostic biomarker. | None |
| Results concluded that MALAT1 functioned as an oncogene in RCC by sponging miR-429, acting as its competing endogenous RNA (ceRNA). | None |