Sentence and cancer type
Showing 121-140 of 204 items.
SentenceCancertype
Sensitivity of human cells bearing oncogenic mutant kit isoforms to the novel tyrosine kinase inhibitor INNO-406. None
Single-molecule conformational analysis of G-quadruplex formation in the promoter DNA duplex of the proto-oncogene c-kit. None
Dysregulated kit function is an important component of oncogenesis in a large number of neoplastic disorders, including systemic mastocytosis.None
Trisubstituted isoalloxazines as a new class of G-quadruplex binding ligands: small molecule regulation of c-kit oncogene expression. None
Kit oncogenic forms are responsible for ezrin phosphorylationNone
Expression of proto-oncogene C-kit and correlation with morphological evaluations in canine cutaneous mast cell tumors. None
Oncogenic and ligand-dependent activation of KIT/PDGFRA in surgical samples of imatinib-treated gastrointestinal stromal tumours (GISTs). None
Kit K641E oncogene up-regulates Sprouty homolog 4 and trophoblast glycoprotein in interstitial cells of Cajal in a murine model of gastrointestinal stromal tumours. None
Oncogenic signaling from the hematopoietic growth factor receptors c-Kit and Flt3. None
A G-rich sequence within the c-kit oncogene promoter forms a parallel G-quadruplex having asymmetric G-tetrad dynamics. None
The aberrant localization of oncogenic kit tyrosine kinase receptor mutants is reversed on specific inhibitory treatment. None
Response to imatinib mesylate depends on the presence of the V559A-mutated KIT oncogene. None
Expression of activated STAT5 in neoplastic mast cells in systemic mastocytosis: subcellular distribution and role of the transforming oncoprotein KIT D816V. None
the ETS family member ETV1 is highly expressed in the subtypes of interstitial cells of Cajal sensitive to oncogenic KIT mediated transformation, and is required for their developmentNone
Activating mutations, specifically in NRAS, are found exclusively in advanced forms of systemic mastocytosis and may precede the proto-oncogene protein c-kit D816V mutation in clonal development.None
Clonal analysis of NRAS activating mutations in KIT-D816V systemic mastocytosis. None
Mechanisms of STAT protein activation by oncogenic KIT mutants in neoplastic mast cells.None
Mechanisms of STAT protein activation by oncogenic KIT mutants in neoplastic mast cells. None
The high rate of c-Kit/PDGFRA coexpression suggests that both receptors are involved in oncogenicity in gastrointestinal stromal tumorsNone
Eng mRNA was up-regulated in Ba/F3 cell lines stably expressing various oncogenic Kit mutations. This effect appeared to be independent of Kit activation.None