Sentence and cancer type
Showing 581-600 of 831 items.
SentenceCancertype
Data indicate that all deltaWT tumors had activating mutations in KRAS, whereas only 69% of deltaKO tumors did, suggesting that PKCdelta acts as a tumor promoter downstream of oncogenic K-ras while acting as a tumor suppressor in other oncogenic contexts.None
Rac1 is essential for K-Ras driven epithelial cell hyperproliferation and that Rac1 activity is elevated in tissues expressing mutant oncogenic K-Ras.None
Impact of oncogenic K-RAS on YB-1 phosphorylation induced by ionizing radiation. None
Syndecan-1 and -4 differentially regulate oncogenic K-ras dependent cell invasionNone
Accumulation of p21ras.GTP in response to stimulation with epidermal growth factor and oncogene products with tyrosine kinase activity. None
p21Waf1 is required for complete oncogenic transformation of mouse embryo fibroblasts by E1Aad5 and c-Ha-ras oncogenes. None
Genotype markers and proto-oncogene analysis in the CD30-positive malignant histiocytosis DEL cell line with t(5;6)(q35;p21). None
Inhibition of miR-193a expression by Max and RXRalpha activates K-Ras and PLAU to mediate distinct aspects of cellular transformation. None
Rb encodes a tumor suppressor that attenuates progression of oncogenic Kras-induced carcinogenesis in the pancreas by mediating the senescence response and promoting activity of the tumor suppressor p53.None
mitochondrial functional loss may be mediated by oncogenic K-Ras-induced mitophagy during early tumorigenesis even in the absence of hypoxiaNone
Under serum-starved conditions, the expression level of RRM2 protein increased in HCT116 cells compared to HKe3 cells (HCT116 cells with a disruption in oncogenic KRAS), and the re-expression of KRAS in HKe3 cells induced the expression of RRM2.None
Kinetic evidence of a rapid activation of phosphatidylcholine hydrolysis by Ki-ras oncogene. Possible involvement in late steps of the mitogenic cascade. None
K-ras oncogene expression in Xenopus laevis. None
ras-induced down-regulation of caspase-2 represents a novel mechanism by which oncogenic Ras protects malignant intestinal epithelial cells from anoikisNone
Ki-ras oncogene mutations in non-HPV-associated anal carcinoma. None
Photoactivated cationic alkyl-substituted porphyrin binding to g4-RNA in the 5 -UTR of KRAS oncogene represses translation. None
This is the first description of an oncogenic gene fusion of KRAS, one of the most studied proto-oncogenes.None
Effect of KRAS oncogene substitutions on protein behavior: implications for signaling and clinical outcome. None
Report of oncogenic BRAF/KRAS mutations in sporadic glomus tumors.None
Detection of point mutations in KRAS oncogene by real-time PCR-based genotyping assay in GIT diseases. None