| In the presence of oncogenic Ras, inflammatory stimuli trigger an NF-kappaB-mediated positive feedback mechanism involving Cox-2 that amplifies Ras activity to pathological levels. | None |
| Oncogenic KRAS and BRAF activation of the MEK/ERK signaling pathway promotes expression of dual-specificity phosphatase 4 (DUSP4/MKP2) resulting in nuclear ERK1/2 inhibition. | None |
| expression of these oncogenes markedly stimulated ERK1/2 activities and morphologically transformed IECs. | None |
| Oncogenic KRAS impairs EGFR antibodies efficiency by C/EBPbeta-dependent suppression of EGFR expression. | None |
| a NUPR1/RELB/IER3 stress-related pathway that is required for oncogenic Kras(G12D)-dependent transformation of the pancreas. | None |
| Our results identify overexpression of S100A8-S100A9 in neurons as an early step in oncogenic Kras-induced gliosis. | None |
| Cancer cells expressing oncogenic KRAS were found to be highly dependent on the transcription factor GATA2 and the DNA replication initiation regulator CDC6. | None |
| These results suggest that maintaining MIST1 activity in Kras(G12D)-expressing acinar cells can partially mitigate the transformation activity of oncogenic KRAS. | None |
| GeLC-MRM quantitation of mutant KRAS oncoprotein in complex biological samples. | None |
| p38gamma Mitogen-activated protein kinase signals through phosphorylating its phosphatase PTPH1 in regulating ras protein oncogenesis and stress response. | None |
| Interplay between oncogenic K-Ras and wild-type H-Ras in Caco2 cell transformation. | None |
| Oncogenic K-Ras regulates bioactive sphingolipids in a sphingosine kinase 1-dependent manner | None |
| Reverse engineering a hierarchical regulatory network downstream of oncogenic KRAS. | None |
| Oncogenic Ras may play a role in epithelial mesenchymal transition via the ERF and regulation of Semaphorin-7a. | None |
| Data show that Med23 deficiency in fibroblasts selectively inhibited the oncogenic transformation induced by Ras | None |
| both the PI3K and Raf pathways are necessary for the expression of IL-11 in oncogenic Ras-mutated cells | None |
| Oncogenic K-Ras promotes the activation of wild-type H- and N-Ras and this activation is mediated by oncogenic K-Ras-dependent allosteric stimulation of Sos. | None |
| Haploinsufficiency of Nkx2-1 in combination with oncogenic Kras(G12D) caused pulmonary tumors in mice that were phenotypically similar to human mucinous adenocarcinomas. | None |
| ASPP1 and ASPP2 cooperate with oncogenic RAS to enhance the transcription and apoptotic function of p53. | None |
| 4-Bromo-2-(piperidin-1-yl)thiazol-5-yl-phenyl methanone (12b) inhibits Na+/K(+)-ATPase and Ras oncogene activity in cancer cells. | None |