| Phosphorylation at Ser-181 of oncogenic KRAS is required for tumor growth. | None |
| Oncogenic KRAS plays a central role in controlling multiple metabolic changes such as stimulation of glucose uptake, differential channeling of glucose intermediates, reprogrammed glutamine metabolism, increased autophagy, and macropinocytosis. (Review) | None |
| Neutralizing monoclonal antibody against ras oncogene product p21 which impairs guanine nucleotide exchange. | None |
| Data show that proteinase-activated receptor (PAR)-2-dependent inflammatory signaling as an essential component of matriptase-mediated and potentiation of ras-mediated oncogenesis. | None |
| Functional phosphoproteomics of oncogenic KRAS signaling. | None |
| This study investigated the proteome modulated by oncogenic KRAS in immortalized airway epithelial cells. | None |
| expression of oncogenic KRAS shifts the balance of DNA repair toward the highly error-prone alternative nonhomologous end-joining pathway. | None |
| ADM is a new target of oncogenic KRAS in the setting of hypoxia | None |
| Non-covalent interactions of the carcinogen (+)-anti-BPDE with exon 1 of the human K-ras proto-oncogene. | None |
| Detection of point mutations of K-ras oncogene and p53 tumor-suppressor gene in sputum samples. | None |
| Human KRAS oncogene expression in meningioma. | None |
| Findings demonstrated that oncogenic K-Ras activates the signaling cascade p38/PDPK1/PKCdelta/p47(phox)/NOX1 for ROS generation and consequent malignant cellular transformation. | None |
| Fos expression protects osteoblasts from RS and DNA damage likely through upregulation of Chk1 and facilitates transformation by Ras/E1A oncogenes. | None |
| findings identified Yap as a critical oncogenic KRAS effector and a promising therapeutic target for PDAC and possibly other types of KRAS-mutant cancers | None |
| In situ selectivity profiling and crystal structure of SML-8-73-1, an active site inhibitor of oncogenic K-Ras G12C. | None |
| Nupr1 aids oncogenic Kras to bypass senescence in a manner that cooperatively promotes pancreas intraepithelial neoplasia formation. | None |
| CDCP1 protein induced by oncogenic Ras/Erk signaling is essential for Ras-mediated metastatic potential of cancer cells. | None |
| Interaction of v-Ki-ras oncogene and interferon-gamma in the control of histocompatibility antigen expression in mouse fibroblasts. | None |
| Data show that caveolin-1 is necessary for optimal KSR1-dependent ERK activation by growth factors and oncogenic Ras. | None |
| results indicate MTH1 is a novel and critical component of oncogenic KRAS-associated malignancy and its inhibition is likely to yield significant tumor-suppressive outcomes in KRAS-driven tumors. | None |