Sentence and cancer type
Showing 661-680 of 831 items.
SentenceCancertype
A high-throughput assay for small molecule destabilizers of the KRAS oncoprotein. None
mTORC1 pathway and the oncogenic Ras/Raf/MEK/extracellular signal-regulated kinase (ERK) pathway cooperate to restrict eEF2K activity.None
A functional genomic approach identifies FAL1 as an oncogenic long noncoding RNA that associates with BMI1 and represses p21 expression in cancer. None
Carcinogenic ability of possibly through oncogenic mutation of gene. None
IER3 supports KRASG12D-associated oncogenesis in the pancreas by sustaining ERK1/2 phosphorylation via phosphatase PP2A inhibition.None
Molecular cloning of the 25 kbp region upstream of exon 0 of the human Ki-ras oncogene and its conservation in transformed mouse NIH 3T3 cells. None
Oncogenic Ras stimulates Eiger/TNF exocytosis to promote growth.None
Novel oncogene and tumor suppressor mutations in KIT and PDGFRA wild type gastrointestinal stromal tumors revealed by next generation sequencing. None
Oncogenic STRAP functions as a novel negative regulator of E-cadherin and p21(Cip1) by modulating the transcription factor Sp1. None
Transcriptional activation of cKi-ras proto-oncogene resulting from retroviral promoter insertion. None
p21-activated kinase 4: a druggable target in the elusive oncogenic KRAS pathway?. None
Direct inhibition of oncogenic KRAS by hydrocarbon-stapled SOS1 helices. None
Expression of ras oncogene p21 during human fetal development as determined by monoclonal antibodies RAP-5, Y13-259, and DWP. None
oncogenic K-Ras is able to induce significant alterations in mitochondrial protein expression, and identified NDUFAF1 as an important molecule whose low expression contributes to mitochondrial dysfunction induced by K-Ras.None
The Akt1(Myr)/KRas(G12D) model holds promise for delineating the tumor biology and biomarkers critical for understanding their cooperation in cancer oncogenesis and future targeting in therapeutic strategies.None
Expression of ki-ras oncogene in tumor cell variants exhibiting different metastatic capabilities. None
Casein kinase 1alpha is a key negative regulator of oncogenic RAS-induced autophagy. Depletion or pharmacologic inhibition of CK1alpha enhanced autophagic flux in oncogenic RAS-driven human fibroblasts and multiple cancer cell lines.None
Our results suggest that DNMT3A mutations and oncogenic RAS cooperate to regulate hematopoietic stem and progenitor cells and promote myeloid malignancies.None
miR-155 plays an important role in oncogenic K-Ras transformation mediated by cellular redox regulationNone
Oncogene-induced senescence underlies the mutual exclusive nature of oncogenic KRAS and BRAF. None