| data suggest that mutations of the k-ras oncogene may induce activation of ERK1/2 in colorectal carcinoma | colorectal, |
| Characterization of a novel oncogenic K-ras mutation in colon cancer. | colorectal, |
| Knockdown of mutant K-ras expression by adenovirus-mediated siRNA inhibits the in vitro and in vivo growth of lung cancer cells. | lung, |
| K-ras oncogene mutations in rat colon tumors induced by N-methyl-N-nitrosourea. | colorectal, |
| the Nestin cell lineage is highly responsive to Kras oncogenic activation and may represent the elusive progenitor population in which pancreatic intraepithelial neoplasia arises | pancreatic, |
| NRP-1 expression was augmented threefold during malignant transformation of ovarian epithelial cells with oncogene ras, suggesting an association between NRP-1 and oncogenesis. | ovarian, |
| K-ras oncogene silencing strategy reduces tumor growth and enhances gemcitabine chemotherapy efficacy for pancreatic cancer treatment. | pancreatic, |
| Targeting mutant k-ras through specific siRNA might be effective for k-ras oncogene silencing and pancreatic tumor growth inhibition. | pancreatic, |
| oncogenic K-RAS/ERK in pancreatic adenocarcinoma facilitates TGFbeta-induced transcriptional down-regulation of the tumor suppressor PTEN in a SMAD4-independent manner | pancreatic, |
| High-degree tumor budding and podia-formation in sporadic colorectal carcinomas with K-ras gene mutations. | colorectal, |
| study of point mutations in RAS oncogenes in papillary thyroid carcinoma; 2 mutations found (GAA/CAA at codon 31 of K-RAS & CAA/CAC at codon 61 of N-RAS); data confirm previous studies, showing RAS mutations are more rare in PTC than follicular neoplasms | neoplasm,thyroid, |
| Prevalence of RAS point mutations in papillary thyroid carcinoma; a novel mutation at codon 31 of K-RAS. | thyroid, |
| The present data suggests that RasGRP1 participates in skin carcinogenesis via biochemical activation of endogenous wild-type Ras and predisposes to malignant progression in cooperation with Ras oncogenic signals. | skin, |
| [Mutations in the 61st codon of the c-Ki-ras oncogene during transplacental lung tumor induction in mice and their difference in spontaneous and induced tumors]. | lung, |
| Correlation between the expression of the P21 ras oncogene product and the biological behavior of bladder tumors. | bladder, |
| Pten inactivation cooperated with oncogenic K-ras in promoting lung tumorigenesis. | lung, |
| Cigarette smoking and KRAS oncogene mutations in sporadic colorectal cancer: results from the Netherlands Cohort Study. | colorectal, |
| Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon. | colorectal, |
| Relationship between overexpression of ras p21 oncoprotein and K-ras codon 12 and 13 mutations in Turkish colorectal cancer patients. | colorectal, |
| [Molecular pathologic KRAS mutation analysis. A prerequisite of effective antibody treatment for metastasized colorectal cancer]. | colorectal, |