| Suggest that miR-1 and miR-145 act as tumor suppressor microRNAs in gallbladder cancer. | bladder, |
| This study provides evidence for hsa-miR-1 to play tumor suppressive roles via downregulating lncRNA UCA1 in bladder cancer | bladder, |
| miR-1 is downregulated in ovarian cancer tissues, and may play a tumor suppressive role by inhibiting c-Met expression and its effects on the regulation of cell proliferation, migration and invasion | ovarian, |
| Data show that miR-1 is tumor suppressive miRNA in glioblastoma (GBM). miR-1 is expressed at relatively low levels in GBM, and high miR-1 expression is associated with better patient survival in glioma. Its ectopic expression in GBM cells inhibited cell proliferation and migration. Expression of miR-1 in GBM cell lines directly targets fibronectin. | GBM,glioblastoma,glioma, |
| This study, we performed a comprehensive analysis of putative human miRNA oncogenes and tumor suppressors. We found that miRNA oncogenes and tumor suppressors clearly show different patterns in function, evolutionary rate, expression, chromosome distribution, molecule size, free energy, transcription factors, and targets. | None |