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Cancertype
microRNA-126 Is a Tumor Suppressor of Granulosa Cell Tumor Mediated by Its Host Gene EGFL7
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The present study revealed that miR1263p plays a role as a tumor suppressor in regulating TNBC cell activities by targeting RGS3.
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Results show that miRNA-126 orchestrates an oncogenic program in B-ALL by downregulating p53-dependent pathways enabling evasion of senescence, cell-cycle arrest and apoptosis, and maintaining blasts in a proliferative B cell precursor state.
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