| microRNAs that jointly act as tumor suppressors in prostate carcinoma | prostate, |
| the data reported here demonstrate that miR-130a is an important tumor suppressor in breast cancer | breast, |
| miR130a functions as tumor suppressors. Levels of miR-130a expression in chronic myeloid leukemia are significantly lower in poor prognostic subgroups, defined by prognostic factors including mutated BCR/ABL status, p53 and ATM deletions and p53 mutations | leukemia, |
| miR-130a is an epigenetically regulated miRNA involved in regulation of key molecular and phenotypic features of prostate carcinogenesis, acting as a tumour suppressor miRNA by targeting SEC23B and DEPDC1. | prostate, |
| MiR-130 exerts tumor suppressive function on the tumorigenesis of human non-small cell lung cancer by targeting PTEN | lung, |
| these results demonstrated that miR130a functioned as a tumor suppressor in osteosarcoma, partially via targeting ZEB1. | osteosarcoma, |
| study demonstrate that miR-130a may function as a tumor suppressor in glioma | glioma, |
| miR-130a-3p is a tumor suppressor in esophageal cancer. Based on the findings from this study and others, we verified that miR-130a-3p suppresses the function of TGF-beta/SMAD4 signal-induced EMT and the invasion and migration in EC-1 cell lines depended on SMAD4. | esophageal, |
| The oncogenic role of microRNA-130a/301a/454 in human colorectal cancer via targeting Smad4 expression. | colorectal, |
| miR-130a was identified as an oncogene that promotes gastric cancer tumorigenesis by targeting RUNX3. | gastric, |
| miR130a can regulate FOXF2 and function as an oncogene in colorectal cancer. | colorectal, |
| our research indicated that miR-130a functions as an oncogene by targeting TFPI2, miR-130a inhibition reduced the growth and angiogenesis of hemangioma by inactivating the FAK/PI3K/Rac1/mdm2 pathway | None |
| Results indicate miR-130a as an oncogenic miRNA that targets PTEN to drive malignant cell survival and tumor growth. | None |