| the tumor suppressor role of miR-133a in lung cancer | lung, |
| Suggest that miR-133a is downregulated in gastric cancer and functions as a tumor suppressor in vitro and in vivo partly by repressing IGF1R. | gastric, |
| miR-133b/a-3p acts as a tumor suppressor in gastric cancer by directly targeting Mcl-1 and Bcl-xL. | gastric, |
| Study finds miR-133a expression significantly downregulated in breast cancer (BC) tissues and cell lines and, significantly associated with advanced clinical stage, lymph node metastasis, as well as shorter survival time of BC patients. Also, the study demonstrates that miR-133a acts as a tumor suppressor in breast cancer partly at least via targeting LASP1. | breast, |
| Study indicated that miR-133a might act as a tumor suppressor and be a valuable independent prognostic and diagnostic biomarker for non-small cell lung cancer (NSCLC), and NSCLC patients with high expression of miR-133 might have a better prognosis.[meta-analysis] | lung, |