| findings show miR-141 is downregulated in pancreatic cancer and the level of expression is associated with overall survival of pancreatic cancer patients; concluded that miR-141 targets MAP4K4 and acts as a tumor suppressor in pancreatic cancer cells | pancreatic, |
| miR-141 is an independent prognostic factor for pancreatic ductal adenocarcinoma patients, and functions as a tumor suppressor gene by targeting YAP1. | pancreatic, |
| miR-141 functions as a tumor suppressor and inhibits the migration and invasion of hepatocellular carcinoma cells by targeting Tiam1. | liver, |
| miR-141 functioned as a tumor suppressor via ZEB2 targeting in hepatocellular carcinoma | liver, |
| Results show that miR-141 functions as a tumor suppressor in hepatocellular carcinoma cells through the inhibition of HNF-3beta translation. | liver, |
| miR-141 is a potent tumor suppressor in the stomach, and its growth inhibitory effects are, in part, mediated through its downstream target gene, TAZ. | gastric, |
| Oncologic risk is increased in myotonic dystrophy type 1 (DM1), especially in women and for gynecologic, brain, and thyroid cancer. Expression of the miRNA-200/miRNA-141 tumor suppressor family is decreased in women with DM1. | brain,thyroid, |
| miR-141-3p functions as a tumor suppressor modulating activating transcription factor 5 in glioma | glioma, |
| Results show that inhibition of miR-141 enhanced colorectal cancer (CRC) cell proliferation and migration and suggest that miR-141 functions as a tumor suppressor through ZEB2 and HGFR in CRC cells. | colorectal, |
| MiR-141-3p functions as a tumor suppressor through directly targeting ZFR in non-small cell lung cancer | lung, |
| MicroRNA-141-5p Acts as a Tumor Suppressor via Targeting RAB32 in Chronic Myeloid Leukemia | leukemia, |
| This study, we performed a comprehensive analysis of putative human miRNA oncogenes and tumor suppressors. We found that miRNA oncogenes and tumor suppressors clearly show different patterns in function, evolutionary rate, expression, chromosome distribution, molecule size, free energy, transcription factors, and targets. | None |
| The crucial role of DNA-dependent protein kinase and myelin transcription factor 1-like protein in the miR-141 tumor suppressor network. | None |
| MicroRNA-141-3p functions as an oncogene in cervical cancer by repressing FOXA2. | cervical, |