| Regulation of UHRF1 by dual-strand tumor-suppressor microRNA-145 (miR-145-5p and miR-145-3p): Inhibition of bladder cancer cell aggressiveness | bladder, |
| miR-145 acts as a tumor suppressor by directly reducing expression of FLI-1, and the miR-145/FLI-1 pathway is important for tumor progression in osteosarcoma | osteosarcoma, |
| MicroRNA-145 functions as a tumor suppressor by targeting matrix metalloproteinase 11 and Rab GTPase family 27a in triple-negative breast cancer | breast, |
| Restitution of Tumor Suppressor MicroRNA-145 Using Magnetic Nanoformulation for Pancreatic Cancer Therapy | pancreatic, |
| MiR-145 functions as a tumor suppressor via regulating angiopoietin-2 in pancreatic cancer cells | pancreatic, |
| These results suggested that miR145 might act as a tumor suppressor during the process of colorectal cancer malignant transformation by interacting with ERG. | colorectal, |
| Study found that p70S6K1 plays an important role in gemcitabine chemoresistence. MiR-145 is a tumor suppressor which directly targets p70S6K1 for inhibiting its expression in pancreatic adenocarcinoma. | pancreatic, |
| Dual-strand tumor-suppressor microRNA-145 (miR-145-5p and miR-145-3p) coordinately targeted MTDH in lung squamous cell carcinoma | lung, |
| MicroRNA-145 exerts tumor-suppressive and chemo-resistance lowering effects by targeting CD44 in gastric cancer | gastric, |
| The study concluded that the expression modulation of tumor suppressors MIR-375 and MIR-145, and oncomiR MIR-224 have the ability to induce apoptosis of colorectal carcinoma cells through regulation of apoptosis mediating genes MTDH, MAP3K1, PDK1, BCL-XL and BAX. | colorectal, |
| Tumor-suppressive miR-145 co-repressed by TCF4-?-catenin and PRC2 complexes forms double-negative regulation loops with its negative regulators in colorectal cancer | colorectal, |
| Passenger strand of miR-145-3p acts as a tumor-suppressor by targeting MYO1B in head and neck squamous cell carcinoma | HNSC, |
| Exportin 1 (XPO1) inhibition leads to restoration of tumor suppressor miR-145 and consequent suppression of pancreatic cancer cell proliferation and migration | pancreatic, |
| Oncogenic HBXIP is a new direct target of tumor suppressive miR-145. Our findings reveal that miR-145-targeting HBXIP could be a potential therapeutic target in breast cancer. | breast, |
| MicroRNA-145 acts as a tumor suppressor in human esophageal squamous cell carcinoma by targeting PLCE1. | esophageal, |
| circOMA1 promotes Nonfunctioning pituitary adenomas progression by acting as the sponge of tumor suppressor miR-145-5p to regulate the TPT1 signaling pathway. | pituitary, |
| Profiling of gallbladder carcinoma reveals distinct miRNA profiles and activation of STAT1 by the tumor suppressive miRNA-145-5p. | bladder, |
| These findings indicate that microRNA-145-5p functions as a novel tumor suppressor through targeting RAB18, suggesting that microRNA-145-5p might be a potential new therapeutic molecule for the treatment of hepatocellular carcinoma. | liver, |
| The miR-143/145 Cluster, a Novel Diagnostic Biomarker in Chondrosarcoma, Acts as a Tumor Suppressor and Directly Inhibits Fascin-1 | sarcoma, |
| MiR-145 functions as a tumor suppressor in Papillary Thyroid Cancer by inhibiting RAB5C | thyroid, |