| This study, we performed a comprehensive analysis of putative human miRNA oncogenes and tumor suppressors. We found that miRNA oncogenes and tumor suppressors clearly show different patterns in function, evolutionary rate, expression, chromosome distribution, molecule size, free energy, transcription factors, and targets. | None |
| Loss of the tumor-suppressive miR-143/145 cluster enhanced cancer cell migration and invasion in PCa through directly regulating GOLM1. | None |
| data indicate that miR-145 and miR-451 act as tumor suppressors in adipose tissue | None |
| miR-451 behaves as a tumor suppressor, probably by targeting the IL6R pathway | None |
| miR-145 may act as a tumor suppressor and contributes to the progression of OS through targeting ROCK1. | None |
| our findings indicate that miR-145 is a tumour suppressor that affects invasive and metastatic properties of NPC via the miR-145/Smad3 axis, leading us to propose that miR-145 overexpression might be a potential therapeutic strategy of NPC intervention. | None |
| Expression of oncogenic miR-17-92 and tumor suppressive miR-143-145 clusters in basal cell carcinoma and cutaneous squamous cell carcinoma | None |
| study demonstrates that miR-143 and -145 have functional properties and expression patterns typical for tumor suppressors, but the function is influenced by cellular factors such as cell type and miRNA cotransfection | None |
| The results of the present study indicated that miRNA145 may function as a tumor suppressor and may have a potential to be a diagnostic and predictive biomarker, and a therapeutic target for treatment of BC. | None |
| Tumor suppressor miR-145-5p sensitizes prolactinoma to bromocriptine by downregulating TPT1 | None |
| MYPT1 knockdown by siRNAs reproduced miR-145 effects suggesting miR-145 as a tumor suppressor through MYPT1 targeting. | None |
| These results highlight that the Ago2 protein in cancer cells strictly dictates miR-145-5p tumor suppressor activity. | None |
| The present study revealed an antioncogenic role of miR145 in gastric carcinoma via inhibition of FSCN1, and suggested that miR145 may be used for the treatment of gastric carcinoma. | gastric, |