| Suggest that methylation-sensitive miRNA, miR-149, may play an important role as a tumour suppressor in colorectal carcinoma via Sp1 pathway. | colorectal, |
| miR-149 as tumor suppressor may be involved in the proliferation and invasion of glioma cells via blockade of the AKT1 signaling. | glioma, |
| These results indicated that miR1495p may act as a tumor suppressor in renal cell carcinoma | kidney, |
| Our findings show that miR-149 functions as a tumor suppressor in osteosarcoma via inhibition of the TWEAK-Fn14 axis and represents a potential therapeutic target in patients with osteosarcoma. | osteosarcoma, |
| The expression levels of lncRNA SNHG8 were dramatically increased in hepatocellular carcinoma (HCC) tissues and cell lines as compared with the adjacent normal tissues, and SNHG8 expression was an independent prognostic factor of tumor recurrence in HCC patients. SNHG8 acted as a sponge of miR-149 and counteracted the tumor suppressive effects of mi R-149. | liver, |
| miR-149 may play a role as tumor suppressor by targeting RAP1B | None |
| MicroRNA-149*, a p53-responsive microRNA, functions as an oncogenic regulator in human melanoma. | skin, |
| Our findings demonstrate that miRNA-149* may serve as an oncogenic regulator in T-cell acute lymphoblastic leukemia by negatively regulating JunB | leukemia, |
| Authors found that DANCR was distributed mostly in the cytoplasm and DANCR functioned as a miRNA sponge to positively regulate the expression of musashi RNA binding protein 2 (MSI2) through sponging miR-149 and subsequently promoted malignant phenotypes of bladder cancer cells, thus playing an oncogenic role in bladder cancer pathogenesis. | bladder, |