| findings establish miR-150 as a novel regulator of MUC4 and a tumor suppressor miRNA in pancreatic cancer | pancreatic, |
| findings show that miR-150 acts as a tumor suppressor through direct repression of multiple oncogenes in MLL-AF9-induced leukemias; miR-150 inhibits MLL-AF9 leukemic cell growth in vitro by induction of apoptosis and blocks the progression of MLL-AF9 leukemias in vivo | leukemia, |
| miR-150 may function as a tumor suppressor and modulate epithelial ovarian cancer cell proliferation, and invasion by directly and negatively regulating ZEB1. | ovarian, |
| these findings suggest that miR-150 functions as a tumor suppressor in Osteosarcoma (OS) partially by targeting IGF2BP1 | osteosarcoma, |
| MicroRNA fingerprints in juvenile myelomonocytic leukemia (JMML) identified miR-150-5p as a tumor suppressor and potential target for treatment | leukemia, |
| miR-150 functions as a tumor suppressor through multiple mechanisms in human leukemia. | leukemia, |
| Histone deacetylase inhibitors inhibit metastasis by restoring a tumor suppressive microRNA-150 in advanced cutaneous T-cell lymphoma | lymphoma, |
| Our results show that two known oncogenic miRs, miR-155 and -92a were upregulated and the tumour suppressor miR-150 was downregulated in the lymph node proliferation centres in chronic lymphocytic leukaemia/small lymphocytic lymphoma | lymphoma, |
| Expression of the miR-150 tumor suppressor is restored by and synergizes with rapamycin in a human leukemia T-cell line | leukemia, |
| MiR-150 could inhibit colorectal cancer progression and serve as a tumor suppressor via inactivating beta-catenin pathway. | colorectal, |
| MicroRNA-150 functions as a tumor suppressor and sensitizes osteosarcoma to doxorubicin-induced apoptosis by targeting RUNX2 | osteosarcoma, |
| miR-150 functions as a tumor suppressor, and that its aberrant downregulation induces continuous activation of the PI3K-AKT pathway, leading to telomerase activation and immortalization of cancer cells. | None |
| The miR150 served as a tumor suppressor of PTC cells by inhibiting growth and metastasis, partially by regulating the expression of the downstream target gene ROCK1. | None |
| This study concluded that miR-150-5p may function as a tumor suppressor in CRC, and miR-150-5p/VEGFA axis may be a potential therapeutic target candidate in CRC treatment. | None |
| Findings indicate the role of miR-150 as an oncogene in lung cancer through the inhibition of SRC kinase signalling inhibitor 1 (SRCIN1) translation. | lung, |
| miR-150 promotes the proliferation and migration of lung cancer cells by targeting SRC kinase signalling inhibitor 1. | lung, |
| ZFAS1 functions as an oncogene in hepatocellular carcinoma progression by binding miR-150 and abrogating its tumor-suppressive function in this setting. | liver, |
| MiR150 plays an important role in the development of lung cancer by serving as an oncogene via the SIRT2/JMJD2A signaling pathway. | lung, |