Sentence and cancer type
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Sentence
Cancertype
These findings support a tumor-suppressive role of miR-152 in the epigenetic aberration of HBV-related HCC and the potential development of miRNA-based targeted approaches for the treatment of HBV-related hepatocellular carcinoma.
liver,
Our findings suggest that miR-152 can act as a tumor suppressor that targets TGFalpha. miR-152 is a promising molecular target that inhibits prostate cancer cell migration and invasion.
prostate,
miR-152 mediates the tumor-suppressive effects that knockdown of XIST exerts in glioblastoma stem cells.
glioblastoma,
miR-152 functions as a tumor suppressor in colorectal cancer by targeting PIK3R3
colorectal,
miR-152-3p might serve as a tumor suppressor in human breast cancer cells via negatively regulating PIK3CA expression to inhibit the activation of AKT and RPS6, leading to suppression of HCC1806 cell proliferation.
liver,breast,
Function of miR?152 as tumor suppressor in oral squamous cell carcinoma cells by targeting c?MET
oral
miR-152 was a tumor suppressor in EC that inhibited proliferation of human endometrial cancer cells via inducing G2/M phase arrest by suppressing CDC25B expression.
endometrial,
MiR-152 functioning as a tumor suppressor that interacts with DNMT1 in nasopharyngeal carcinoma
nasopharyngeal,laryngeal,
miR-148a and miR-152 act as tumor suppressors by targeting IGF-IR and IRS1, and that restoration of miR-148a/152 expression may provide a strategy for therapeutic application to treat BC patients.
None
miR-152 as a tumor suppressor microRNA: Target recognition and regulation in cancer
None