| miR-17-5p functions as a tumor suppressor in cervical cancer cells by targeting tumor protein p53-induced nuclear protein 1. | cervical, |
| Our data indicate that miR-17-5p acts as a tumour suppressor in Triple-negative breast cancer (TNBC)by targeting ETV1, and a low-abundance of miR-17-5p may be involved in the pathogenesis of TNBC. These findings indicate that miR-17-5p may be a therapeutic target for TNBC | breast, |
| findings show miR-17-5p acts specifically at the G1/S-phase cell cycle boundary, by targeting more than 20 genes involved in transition between these phases; miR-17-5p is able to act as both an oncogene & tumor suppressor in different cellular contexts | None |
| Apoptosis induction by antisense oligonucleotides against miR-17-5p and miR-20a in lung cancers overexpressing miR-17-92. | lung, |
| Oncogenic role of miR-17-92 cluster in anaplastic thyroid cancer cells. | thyroid, |
| Antagomir-17-5p abolishes the growth of therapy-resistant neuroblastoma through p21 and BIM. | neuroblastoma, |
| Genetic dissection of the miR-17~92 cluster of microRNAs in Myc-induced B-cell lymphomas. | lymphoma, |
| miR-17-5p Promotes migration of human hepatocellular carcinoma cells through the p38 mitogen-activated protein kinase-heat shock protein 27 pathway. | liver, |
| miR-17-5p promotes human breast cancer cell migration and invasion through suppression of HBP1. | breast, |
| MicroRNA miR-17-5p is overexpressed in pancreatic cancer, associated with a poor prognosis, and involved in cancer cell proliferation and invasion. | pancreatic, |
| Regulation of cancer aggressive features in melanoma cells by microRNAs. | skin, |
| miR-17~92 cooperates with RB pathway mutations to promote retinoblastoma. | retinoblastoma, |
| miR-135b mediates NPM-ALK-driven oncogenicity and renders IL-17-producing immunophenotype to anaplastic large cell lymphoma. | lymphoma, |
| miR-21, miR-17 and miR-19a induced by phosphatase of regenerating liver-3 promote the proliferation and metastasis of colon cancer. | colorectal,liver, |
| Synthetic lethality between Rb, p53 and Dicer or miR-17-92 in retinal progenitors suppresses retinoblastoma formation. | retinoblastoma, |
| Oncogenic microRNA 17-92 cluster is regulated by epithelial cell adhesion molecule and could be a potential therapeutic target in retinoblastoma. | retinoblastoma, |
| Elevated oncofoetal miR-17-5p expression regulates colorectal cancer progression by repressing its target gene P130. | colorectal, |
| miR-17-5p/20a are important markers for gastric cancer and murine double minute 2 participates in their functional regulation. | gastric, |
| Estrogen receptor beta expression induces changes in the microRNA pool in human colon cancer cells. | colorectal, |
| miR-106b-25/miR-17-92 clusters are polycistrons with oncogenic roles in hepatocellular carcinoma [review] | liver, |