| These results indicate that miR-182 targets the CREB1 gene and suppresses gastric adenocarcinoma cell growth, suggesting that miR-182 shows tumor-suppressive activity in human gastric cancer. | gastric, |
| miR-182, a p53 dependent miRNA, suppressed the expression of MITF, BCL2, cyclin D2 and functioned as a potent tumor suppressor in uveal melanoma cells. | skin, |
| Coordinate regulation of FOXO1 by miR-27a, miR-96, and miR-182 in breast cancer cells. | breast, |
| Our findings suggest that miR-182 dys-regulation confers powerful oncogenic potential in the tumourigenesis of high-grade serous ovarian carcinoma. | ovarian, |
| miR-182-5p plays an important role as an oncogene by knocking down RECK and Smad4, resulting in activation of the Wnt-beta-catenin signaling pathway in bladder cancer. | bladder, |
| Oncogenic miRNA-182-5p targets Smad4 and RECK in human bladder cancer. | bladder, |
| MicroRNA-182 promotes cell growth, invasion, and chemoresistance by targeting programmed cell death 4 (PDCD4) in human ovarian carcinomas. | ovarian, |
| The miR-183/-96/-182 cluster is up-regulated in most breast cancer. It functions as an oncogene in breast cancer as it increases cell proliferation and migration. | breast, |
| MiR-182 functions as an anti-oncogene in clear cell renal cell carcinoma, and miR-182-mediated inhibition of cell migration and invasion might be through directly targeting IGF1R. | kidney, |
| oncogenic effect of miR-182 and its reversal by beta-TrCP2 were confirmed in vivo This study suggests that beta-TrCP and miR-182 may be possible biomarkers and targets for early detection and treatment of pancreatic cancer | pancreatic, |
| miR-182 reveals its oncogenic capacity in medullary thyroid carcinoma by directly contributing to the invasive behavior through loss of the tumor suppressive HES1/Notch1 signaling circuit. | thyroid, |
| miR-182 acts as one of oncogenic factor in the progression of prostate cancer by recruiting a mechanism of aberrant activation of Wnt/beta-catenin signaling. | prostate, |
| miR-182 exerted its oncogenic role in CRC by targeting DAB2IP | None |