| our findings established a tumor-suppressive role for miR-186 in the progression of NSCLC. | lung, |
| miR-186 affects the proliferation, invasion and migration of human gastric cancer (GC) by inhibition of Twist1, and could be a tumor suppressor in GC development. Thus, miR-186 may be served as a candidate prognostic biomarker and target for new therapies in human gastric cancer. | gastric, |
| MiR-186-5p is a novel tumor suppressor microRNA that functions to inhibit tumorigenesis of glioblastoma multiforme both in vitro and in vivo. | glioblastoma, |
| The findings demonstrate that miR-186 acts as a tumor suppressor by targeting IGF-1R in glioma. | glioma, |
| Results show that miR186 is suppressed in osteosarcoma (OS) tissues and provide evidence that miR186 functions as a tumor suppressor in OS cells partially by targeting PTTG1 and that HIF1mediated suppression of aerobic glycolysis may be also involved in its suppressive effects. | osteosarcoma, |
| miR-186-5p Functions as a Tumor Suppressor in Human Osteosarcoma by Targeting FOXK1 | osteosarcoma, |
| Our collective results clearly indicate that miR-186 functions as a tumor suppressor in MM, supporting its potential as a therapeutic target for the disease. | None |
| Authors identify that miR-186 serves as a tumor suppressor in OSCC. Downregulation of this microRNA may lead to a higher expression of oncogenic factor SHP2, which leads to activation of growth promoting signaling. | None |
| The Dual Role of miR-186 in Cancers: Oncomir Battling With Tumor Suppressor miRNA | None |
| Our findings suggest miR-186-5p plays an oncogenic role in PCa. Inhibition of miR-186-5p reduced PCa cell proliferation and invasion as well as increased AKAP12 expression. | None |