| Identification and validation of three miRNAs (miR-124, miR-147 and miR-193a-3p) as novel tumor suppressors that co-target EGFR-driven cell-cycle network proteins and inhibit cell-cycle progression and proliferation in breast cancer. | breast, |
| Taken together, our findings provide the first clues regarding the role of miR-193a-3p as a tumor suppressor in lung cancer through the inhibition of ERBB4 translation. | lung, |
| miR-193a-3p is a potential tumor suppressor in malignant pleural mesothelioma | mesothelioma, |
| miR-193a-3p is a Key Tumor Suppressor in Ulcerative Colitis-Associated Colon Cancer and Promotes Carcinogenesis through Upregulation of IL17RD | colorectal, |
| This study confirms the tumor suppressor roles of miR-193a-3p, its downstream target affinity to KRAS and clinical significance in patients with colorectal adenocarcinoma. | colorectal, |
| Results find that miR-193a-3p is down-regulated in BRAF-mutated colorectal cancer and disclose a novel tumor suppressive role for miR-193a-3p in colorectal cancer. | colorectal, |
| Data found that miR-193a is downregulated in metastatic prostate cancer and plays tumor suppressive function in prostate cancer, which was attributed to HOTAIR mediated EZH2 targeting to the promoter of miR-193a. | prostate, |
| MiR-193a-3p functions as a tumour suppressor in human aldosterone-producing adrenocortical adenomas by down-regulating CYP11B2 expression. | adrenocortical, |
| The expression of miR-193a was significantly downregulated in glioblastoma (GBM) tissues and cell lines and correlated with a shorter disease-free survival. Functionally, miR-193a overexpression dramatically suppressed the proliferation, colony formation, migration, and invasion in glioma cells. Thse findings suggested that miR-193a functions as a tumor suppressor in glioma cells by directly targeting NOVA1. | colorectal,GBM,glioblastoma,glioma, |
| Tumor Suppressor Role of hsa-miR-193a-3p and -5p in Cutaneous Melanoma | skin, |
| Liquid Biopsy of Extracellular Vesicle-Derived miR-193a-5p in Colorectal Cancer and Discovery of Its Tumor-Suppressor Functions | colorectal, |
| Our data describe a new molecular mechanism whereby expression of the tumour suppressor gene RASSF1 is controlled in human cells; miR-193a-3p binds directly to the RASSF1-3_UTR, which leads to downregulation of the mRNA and protein levels of the target gene. | None |
| Restoration of miR-193a expression is tumor-suppressive in MYC amplified Group 3 medulloblastoma | None |