| Oncogenic role of miR-17-92 cluster in anaplastic thyroid cancer cells. | thyroid, |
| Genetic dissection of the miR-17~92 cluster of microRNAs in Myc-induced B-cell lymphomas. | lymphoma, |
| MYCN-regulated microRNAs repress estrogen receptor-alpha (ESR1) expression and neuronal differentiation in human neuroblastoma. | neuroblastoma, |
| miR-17~92 cooperates with RB pathway mutations to promote retinoblastoma. | retinoblastoma, |
| miR-21, miR-17 and miR-19a induced by phosphatase of regenerating liver-3 promote the proliferation and metastasis of colon cancer. | colorectal,liver, |
| SOCS1 gene is a direct target of miR-19a, which functions as an oncogenic miRNA in gastric cancer by repressing the expression of tumor suppressor SOCS1. | gastric, |
| these data suggest that miR-19a plays an oncogenic role in the progression of laryngeal squamous cell carcinoma | laryngeal, |
| miR-19a acts as an oncogenic microRNA and is up-regulated in bladder cancer. | bladder, |
| MicroRNA-19a functions as an oncogenic microRNA in non-small cell lung cancer by targeting the suppressor of cytokine signaling 1 and mediating STAT3 activation | lung, |
| Study demonstrated that MicroRNA-19a (miR-19a) upregulation is common in gliomas and that suppression of miR-19a expression inhibits cell proliferation and invasion, which indicates that miR-19a may act as an oncogene in gliomas. | glioma, |
| Oncogenic miR-19a and miR-19b were up-regulated in lung cancer stem cells which modulated cancer cells activity. miR-19 activated Wnt/beta-catenin pathway via directly targeting Glycogen Synthase Kinase 3 beta. Sulforaphane suppressed lung cancer stem cells through down-regulating miR-19 and inhibiting Wnt/beta-catenin pathway activation. | lung, |
| A microRNA polycistron as a potential human oncogene. | None |
| miR-19 is a key oncogenic component of mir-17-92. | None |
| Genome-wide RNA-mediated interference screen identifies miR-19 targets in Notch-induced T-cell acute lymphoblastic leukaemia. | None |
| we clarify the mode of regulation of the oncogenic miR-19a by PLEKHA7. | None |
| Our results suggest that miR-19a acted as an oncogenic miRNA by targeting PTEN in myeloma. This novel miR-19a/PTEN/AKT axis sheds new light on the mechanisms underlying apoptosis and invision and may provide potentially therapeutic targets for the treatment of myeloma. | None |