| Suppression of the Kindlin-2-integrin beta1-AKT regulatory axis is an alternative mechanism underlying the tumor suppressor function of miR-200b in esophageal squamous cell carcinoma. | esophageal, |
| The tumor suppressive miR-200b subfamily is an ERG target gene in human prostate tumors | prostate, |
| MicroRNA-200b acts as a tumor suppressor in osteosarcoma via targeting ZEB1 | osteosarcoma, |
| Results provide evidence that miR-200b acts as a tumor suppressor in glioma through the inhibition of LDHA both in vitro and in vivo. | glioma, |
| these results define opposing roles for oncogenic ARHGAP18 and tumor suppressive miR-200b in determining triple-negative breast cancer cell migration and metastatic prowess | breast, |
| This study, we performed a comprehensive analysis of putative human miRNA oncogenes and tumor suppressors. We found that miRNA oncogenes and tumor suppressors clearly show different patterns in function, evolutionary rate, expression, chromosome distribution, molecule size, free energy, transcription factors, and targets. | None |
| miR-200b, a frequently deregulated tumor suppressive miRNA in a wide spectrum of cancers, suppresses multiple key cell cycle regulators and mitigates the Wnt/beta-Catenin signaling. | None |