| miR-204-5p acts as a tumor suppressor in colorectal cancer through inhibiting RAB22A and reveal RAB22A to be a new oncogene and prognostic factor for colorectal cancer. | colorectal, |
| The miR-204 acts as a tumour suppressor by inhibiting NUAK1 expression in NSCLC. | lung, |
| miR-204-5p acts as a tumor suppressor in gastric cancer through inhibiting USP47 and RAB22A. | gastric, |
| miR-204 may act as a tumor suppressor by directly targeting ATF2 in non-small cell lung cancer | lung, |
| our findings revealed that miR-204 functions as a tumor suppressor in non-small-cell lung carcinoma (NSCLC) by targeting JAK2, and that miR-204 may therefore serve as a biomarker for the diagnosis and treatment of NSCLC. | lung, |
| Tumor suppressor miRNA-204-5p promotes apoptosis by targeting BCL2 in prostate cancer cells | prostate, |
| miR-204-5p acts as a tumor suppressor by targeting matrix metalloproteinases-9 and B-cell lymphoma-2 in malignant melanoma | skin,lymphoma, |
| These findings suggested that miR-204 might serve as a tumor suppressor in the development of cervical cancer by directly targeting EphB2. | cervical, |
| Study revealed that miR- 204 acted as a potent lung tumor suppressor in lung cancer by targeting the FZD4:rs713065 C allele, therefore inhibiting FZD4 expression and cellular function in the Wnt-signaling-driven tumor progression. | lung, |
| Study identified miR-204 as a tumor suppressor miRNA that inhibited a subnetwork of oncogenes strongly associated with MYCN-amplified neuroblastoma and poor patient outcome. MYCN bound to the miR-204 promoter and repressed miR-204 transcription. Conversely, miR-204 directly bound MYCN mRNA and repressed MYCN expression. | neuroblastoma, |
| miR-204 functions as a tumor suppressor gene, at least partly by suppressing CYP27A1 in glioblastoma | glioblastoma, |
| Tumor Suppressor miRNA-204-5p Regulates Growth, Metastasis, and Immune Microenvironment Remodeling in Breast Cancer | breast, |
| MicroRNA-204-5p is a tumor suppressor and potential therapeutic target in head and neck squamous cell carcinoma | HNSC, |
| MIR-204 is a VHL-regulated tumor suppressor acting by inhibiting macroautophagy, with MAP1LC3B (LC3B) as a direct and functional target. | None |
| Results found dualistic miR-204 effects, either acting as a tumor suppressor on c-MYB, or as an oncomiR on ETS1. RUNX2 and ETS1 regulation by miR-204 was ERG fusion dependent, demonstrating regulatory circuitry disruption in advanced metastatic models. | None |