| miR-1/206 suppressed c-Met expression in rhabdomyosarcoma and could function as a potent tumor suppressor in c-Met-overexpressing tumors. | sarcoma, |
| Studies indicate that loss of tumor suppressor miR-206, and the overexpression of oncogenic miR-21 have been observed in many breast cancers. | breast, |
| tumour suppressive role of miR-206 in the progression of breast cancer, at least partly via up-regulation of the expression of cyclin D2 | breast, |
| These observations support hsa-miR-206 as a tumor suppressor in melanoma and identify Cyclin C, Cyclin D1, and CDK4 as miR-206 targets. | skin, |
| Taken together, our results uggest that miR-206 is a potential regulator of apoptosis, the cell cycle and migration in HepG2 cells and that it has the potential for use in the targeted therapy of HCC and is a novel tumor suppressor | liver, |
| Upregulation of miR-206 inhibited cancer cell proliferation and migration, blocked the cell cycle, and activated apoptosis. These results support miR-206 as a tumor suppressor in colorectal cancer. | colorectal, |
| miR-206 suppressed c-Met expression in gastric cancer and could function as a potent tumor suppressor in c-Met overexpressing tumors. | gastric, |
| A crucial tumor suppressive role was identified for miR-206 in laryngeal squamous cell carcinoma growth. | laryngeal, |
| miR-206 functioned as a tumor suppressor in the progression of colorectal cancer(CRC) by targeting FMNL2 and c-MET. Restoration of miR-206 expression may represent a promising therapeutic approach for targeting malignant CRC. | colorectal, |
| miR-206 functions as a novel cell cycle regulator and tumor suppressor in clear-cell renal cell carcinoma | kidney, |
| Dual-receptor (EGFR and c-MET) inhibition by tumor-suppressive miR-1 and miR-206 in head and neck squamous cell carcinoma | HNSC, |
| MiR-206 functions as a tumor suppressor and directly targets K-Ras in human oral squamous cell carcinoma [Retraction] | oral |
| MicroRNA-206 acts as a tumor suppressor in bladder cancer via targeting YRDC | bladder, |
| miR-206 functions as a tumor suppressor in regulating the proliferation, migration and invasion of renal cell carcinoma by directly targeting GAK. | kidney, |
| miR-206 and miR-140, as tumor suppressors, induced lung adenocarcinoma cell death and inhibited cell proliferation by modifying oncogenic TRIB2 promoter activity through p-Smad3. | lung, |
| miR-206 is remarkably downregulated and is inversely correlated with CDK9 level in HCC cells. It is evident that miR-206 functions as a tumor suppressor through blocking CDK9-related pathway to induce apoptosis and inhibit HCC cell proliferation. | liver, |
| MicroRNA-206 serves as a tumor suppressor in pediatric acute myeloid leukemia by targeting Cyclin D1 | leukemia,pediatric, |
| Expression of the tumor suppressor miR-206 is associated with cellular proliferative inhibition and impairs invasion in ER??-positive endometrioid adenocarcinoma. | None |
| a novel activity for miR-206 in skeletal muscle differentiation. Cyclin D1 is identified as a major target that further strengthens the tumor suppressor function proposed for miR-206. | None |
| miR-206 suppressed c-Met and Bcl2 expression in NSCLS and could function as a potent tumor suppressor in c-Met/Bcl2-over expressing tumors. | None |