| PTEN-mediated miR-21 regulation is achieved by inhibiting the interaction between the Drosha complex and RNH1, revealing previously unidentified role of PTEN in the oncogenic miR-21 biogenesis | None |
| miR-21 is the most frequently deregulated microRNA in malignancy, and it has oncogenic potential downstream of STAT3. | None |
| Interaction of the oncogenic miR-21 microRNA and the p53 tumor suppressor pathway. | None |
| miR-21 is a key player in oncogenic EMT, its overexpression is controlled by the cooperation of genetic and epigenetic alterations, and its levels, along with ITGbeta4 and PDCD4 expression, could be exploited as a prognostic tool for CRC metastasis. | None |
| PDCD4 and miR-21 are involved in OSC oncogenesis | None |
| miRNA-21, as a proto-oncogene, involved in the process of development and drug resistant of multiple myeloma. Overexpression of miRNA-21 leads to the abnormal change of JAK/STAT-3, NF-kappaB expression. | None |
| PAPD5 and PARN mediate degradation of oncogenic miRNA miR-21. | None |
| Our results identify FBXO11 as a novel miR-21 target gene, and demonstrate that the oncogenic miRNA miR-21 decreases the expression of FBXO11, which normally acts as a tumor suppressor, and thereby promotes tumorigenesis. | None |
| In the presence of oncogenic miR-21 in cancer cells, Ce6-PNA drug gets hybridized with miR-21, resulting in the release of Ce6-PNA from Dex-RGON and subsequent recovery of Ce6 fluorescence and activation of Ce6 as a photosensitizer under near IR irradiation. | None |
| Activation of the oncogenic miR-21-5p promotes HCV replication and steatosis induced by the viral core 3a protein. | None |