| miR-218 expression is reduced in gastric cancer, and may function as a tumor suppressor. | gastric, |
| Data indicate that LASP1 may have an oncogenic function and that it might be regulated by miR-1, miR-133a, and miR-218, which may function as tumor suppressive miRNAs in bladder cancer (BC). | bladder, |
| Our study is the first to demonstrate that miR-218 located on chrosomosme 4p15.31 is a tumor suppressive miRNA in bladder cancer (BC). | bladder, |
| miR-218 on the genomic loss region of chromosome 4p15.31 functions as a tumor suppressor in bladder cancer. | bladder, |
| miR-585 is a tumor suppressor that is often epigenetically silenced in oral squamous cell carcinoma. | oral |
| LASP1 was a direct target of miR-218 in prostate cells.Loss of tumor-suppressive miR-218 enhanced cancer cell migration and invasion in prostate cancer cells through direct regulation of LASP1. | prostate, |
| miRNA-218 acted as a tumor suppressor in pancreatic cancer by inhibiting cell invasion and migration. | pancreatic, |
| Tumor-suppressive microRNAs (miR-26a/b, miR-29a/b/c and miR-218) concertedly suppressed metastasis-promoting LOXL2 in head and neck squamous cell carcinoma | HNSC, |
| Tumor-suppressive miR-218-5p inhibits cancer cell proliferation and migration via EGFR in non-small cell lung cancer | lung, |
| miR-214 and miR-218 function as tumor suppressors in breast cancer, and may become biomarkers and potential therapeutic targets in breast cancer. | breast, |
| Tumor-suppressive microRNA-218 inhibits tumor angiogenesis via targeting the mTOR component RICTOR in prostate cancer | prostate, |
| Studied the tumor suppressive role and antiproliferative effect of MicroRNA-218 in lung cancer cells through targeting of IL-6/STAT3 pathway. | lung, |
| miR218 functions as a tumor suppressor in human glioma. | glioma, |
| miR?218 functions as a tumor suppressor gene in cervical cancer | cervical, |
| MIR218 functions as a tumor suppressor by regulating SH3GL1 expression in medulloblastoma cancer cells. | None |
| The miR-218 acts as a tumor suppressor by targeting many oncogenes related to proliferation, apoptosis and invasion. | None |
| The tumor suppressive role of miR-218 was mediated by negatively regulating branched-chain amino acid transaminase 1 (BCAT1) protein expression. Importantly, overexpression of BCAT1 decreased the chemosensitivity to cis-diaminedichloroplatinum treatment of PC3 and DU145 cells. | None |