| MiR-22 is down-regulated and acts as a tumor suppressor by targeting the Sp1 gene and inhibiting gastric cancer cell migration and invasion. | gastric, |
| Findings showed that miR-22 functioned as tumor suppressor in renal cell carcinoma (RCC) and blocked RCC growth and metastasis by directly targeting SIRT1. | kidney, |
| miR-22 has a tumor suppressor role in breast cancer cells and could be used as a biomarker | breast, |
| LncRNA Sox2OT-V7 promotes doxorubicin-induced autophagy and chemoresistance in osteosarcoma via tumor-suppressive miR-142/miR-22 | osteosarcoma, |
| MiR-22 as a metabolic silencer and liver tumor suppressor | liver, |
| miR-22 acts as a tumor suppressor through direct repression of MYCBP expression and subsequent reduction of oncogenic c-Myc activities. | None |
| this study provides the first evidence that miR-22 restores the cellular senescence program in cancer cells and acts as a tumor suppressor. | None |
| Data indicate that overexpression of CD151 significantly attenuated the tumor suppressive effect of miR-22. | None |
| Data provide the first evidence that de-regulated Jak3/STAT3/STAT5 signalling in CTCL cells represses the expression of the gene encoding miR-22, a novel tumor suppressor miRNA. | None |
| 6-Formylindolo[3,2-b]carbazole (FICZ) Enhances The Expression of Tumor Suppressor miRNAs, miR-22, miR-515-5p, and miR-124-3p in MCF-7 Cells | None |
| The dual action of hsa-miR-125b as a tumor suppressor and hsa-miR-22 as an oncomiR contributed to prostate tumorigenesis by modulations in PI3K/AKT and MAPK/ERK signaling pathways. | prostate, |