Showing 21-23 of 23 items.

Sentence	Cancertype
miR-27a contributed to cell proliferation and invasion by inhibiting TGF-beta-induced cell cycle arrest. These results suggest that miR-27a may function as an oncogene by regulating SMAD2 and SMAD4 in lung cancer.	lung,
CircRNA RAPGEF5 (cRAPGEF5) significantly downregulated in renal cell carcinoma (RCC) tissues and correlated positively with aggressive clinical characteristics and independently predicted poor overall survival and recurrence-free survival. cRAPGEF5 functions as a sponge of oncogenic miR-27a-3p, which facilitates RCC proliferation and migration by targeting the suppressor gene TXNIP.	kidney,
Upregulation of miR-27a contributes to the malignant transformation of human bronchial epithelial cells induced by SV40 small T antigen.	None