| miR-29c may play an important role as a tumor suppressive microRNA in the development and progression of HBV-related hepatocellular carcinoma by targeting TNFAIP3. | liver, |
| miR-29c functions as a tumor suppressor by regulating abnormal SIRT1 activity in liver | liver, |
| miR-29c serves as a tumor metastasis suppressor, which suppresses lung cancer cell adhesion to ECM and metastasis by directly inhibiting integrin beta1 and MMP2 expression | lung, |
| The miR-29s acted as tumour suppressors and directly targeted laminin-integrin signalling in head and neck squamous cell carcinoma. | HNSC, |
| We identified miRNAs efficiently downregulating B7-H3 expression. The expression of miR-29c correlated with survival in breast cancer patients, suggesting a tumour suppressive role for this miRNA. | breast, |
| Results suggest that the IR-responsive miR-29c may function as a tumor suppressor that plays a crucial role in the development of liver carcinoma via targeting WIP1. | liver, |
| Tumor-suppressive microRNAs (miR-26a/b, miR-29a/b/c and miR-218) concertedly suppressed metastasis-promoting LOXL2 in head and neck squamous cell carcinoma | HNSC, |
| miR-29c overexpression could abrogate the tumor progression and inhibit the Sp1/TGF-beta expressions in vivo, indicating that miR-29c could be a tumor suppressor and repress the Sp1/TGF-beta axis-induced EMT in lung cancer. | lung, |
| Results show that MiR-29c expression downregulation was significantly associated with unfavorable prognosis in IIIA-N2 lung adenocarcinoma (LAD). These data provide evidence that miR-29c plays a tumor suppressive role in LAD and its function is mainly mediated by its target-VEGFA. | lung, |
| Tumor suppressor miR-29c regulates radioresistance in lung cancer cells | lung, |
| MicroRNA29c3p acts as a tumor suppressor gene and inhibits tumor progression in hepatocellular carcinoma by targeting TRIM31. | liver, |
| This study, we performed a comprehensive analysis of putative human miRNA oncogenes and tumor suppressors. We found that miRNA oncogenes and tumor suppressors clearly show different patterns in function, evolutionary rate, expression, chromosome distribution, molecule size, free energy, transcription factors, and targets. | None |