| The present study suggested that the tumor suppressor miR30c may be involved in prostate cancer tumorigenesis, possibly via targeting ASF/SF2. [miR30c] | prostate, |
| MiR-30c and MTA1 abnormally expressed in ovarian cancer (OC), which may be related to metastasis of OC. In MiR-30c as a tumor suppressor gene, its expression in OC could lead to reduced expression of MTA1, which may be one of the mechanisms of metastasis of OC cells. | ovarian, |
| MicroRNA-30c functions as a tumor suppressor via targeting SNAI1 in esophageal squamous cell carcinoma | esophageal, |
| Overexpressed miR-30c could weaken osteosarcoma cell_s abilities of viability, proliferation, migration and invasion. MiR-30c could play an important role in tumor suppression for pediatric osteosarcoma progression and metastasis by targeting SOX9 in vitro. | osteosarcoma,pediatric, |
| MiR-30c exerts tumor suppressive functions in colorectal carcinoma by directly targeting BCL9. | colorectal, |
| these data suggest that miR-30C, a tumor suppressor miRNA, contributes to anti-cancer properties of sulfuretin by negatively regulating cyclin D1 and D2, providing important implications of sulfuretin and miR-30C for the therapeutic intervention of human cancers. | None |
| Thus, by balancing Serpine1 expression in ECs downstream of TGF-beta, miR-30c functions as a tumor suppressor in the tumor microenvironment through its ability to promote fibrin degradation and inhibit blood vessel formation. | None |