| MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells. | neuroblastoma, |
| miR-34a is a tumor suppressor gene in human neuroblastoma | neuroblastoma, |
| Results demonstrate that miR-34a acts as a tumor suppressor in p53-mutant glioma cells U251, partially through regulating SIRT1. | glioma, |
| MicroRNA-34a is a potent tumor suppressor molecule in vivo in neuroblastoma. | neuroblastoma, |
| MicroRNA-34 suppresses breast cancer invasion and metastasis by directly targeting Fra-1. | breast, |
| miR-34a may act as a tumor suppressor miRNA of HCC. The strategies to increase miR-34a level might be a critical targeted therapy for HCC in future. | liver, |
| study defines a major metastasis and angiogenesis suppressive role for mir-34a, a microRNA functions as a tumor suppressor in bladder cancer by directly targeting CD44, which would be helpful as a therapeutic approach to block bladder cancer metastasis | bladder, |
| Results show that miR-34a is a tumor suppressor gene. Its high expression level in non-muscle invasive bladder tumors compared to the muscle invasive type is correlated with lower risks of recurrence. | bladder, |
| MiR-34a was down-regulated in colorectal cancer cells and inversely correlated with FMNL2 and E2F5 expressions. Our study suggests that miR-34a is an important tumor suppressor of CRC progression by targeting FMNL2 and E2F5. | colorectal, |
| Tumor-suppressive microRNA-34a inhibits breast cancer cell migration and invasion via targeting oncogenic TPD52 | breast, |
| miR-34a was a tumor suppressor in glioma cells, suppressing cell proliferation and inducing cell apoptosis via targeting of Bcl-2. | glioma, |
| miR-34a, a tumor suppressor gene, is down-regulated in the K-562 cells and chronic myeloid leukemia (CML) patients due to aberrant DNA hypermethylation. c-SRC is a target of miR-34a. | leukemia, |
| Tumor suppressor microRNA-34a inhibits cell migration and invasion by targeting MMP-2/MMP-9/FNDC3B in esophageal squamous cell carcinoma | esophageal, |
| Results provide evidence that miR-34a is a tumor suppressor that regulates glycolysis and immunity in triple negative breast cancer (TNBC) cells by targeting LDHA and PDL1. | breast, |
| MicroRNA-34a functions as a tumor suppressor by directly targeting oncogenic PLCE1 in Kazakh esophageal squamous cell carcinoma | esophageal, |
| our findings provide new insights into the tumor suppressor role of miR-34a by dual-targeting of FOXM1/eEF2K signaling axis and suggest that miR-34a-based gene therapy may be a potential therapeutic strategy in triple-negative breast cancer (TNBC) | breast, |
| Study demonstrated that the expression level of miR34a was reduced in retinoblastoma (RB) tissues significantly associated with poor prognosis. Further data suggest that miR34a may function as a tumor suppressor for RB by targeting MAGEA and altering p53 expression. | retinoblastoma, |
| Effect of Tumor Suppressor MiR-34a Loaded on ZSM-5 Nanozeolite in Hepatocellular Carcinoma: In Vitro and In Vivo Approach | liver, |
| CUL4B contributes to cancer stemness by repressing tumor suppressor miR34a in colorectal cancer | colorectal, |
| miR-34a represents a tumor suppressor gene which is inactivated by CpG methylation and subsequent transcriptional silencing in a broad range of tumors. | None |