| Overexpression of miR-98 functions as a tumor suppressor in gliomas. | glioma, |
| MicroRNA-98 acts as a tumor suppressor in hepatocellular carcinoma via targeting SALL4 | liver, |
| These results suggested that miR-98 functioned as a potential tumor suppressor by regulating Wnt/beta-catenin signal pathway through direct suppression of EZH2 expression and might sever as a potential therapeutic target for HCC patients. | liver, |
| MiR-98 acts as a tumor suppressor in non-small cell lung cancer cells by inhibiting the protein expression of its target gene SALL4. | lung, |
| MiR-98 may act as a tumor suppressor in NSCLC. | lung, |
| Methylation-induced downregulation and tumor-suppressive role of microRNA-98 in glioma through targeting Sal-like protein 4 | glioma, |
| Insulinlike growth factor1 receptor (IGF1R) is a target of tumor suppressor microRNA98 (miR98) in the pathogenesis of retinoblastoma (RB). Expressions of miR98 and IGF1R in tumor tissues are negatively correlated. Restoration of IGF1R reverses the anticancer effects of miR98 on RB cell viability, migration and invasion. | retinoblastoma, |
| miR-93, miR-98, and miR-197 regulate expression of tumor suppressor gene FUS1. | None |
| This study, we performed a comprehensive analysis of putative human miRNA oncogenes and tumor suppressors. We found that miRNA oncogenes and tumor suppressors clearly show different patterns in function, evolutionary rate, expression, chromosome distribution, molecule size, free energy, transcription factors, and targets. | None |
| miR-98 functions as a tumor suppressor in salivary adenoid cystic carcinomas | None |