| MDM2 as a critical effector of the MYCN oncogene in tumorigenesis. | None |
| The oncoprotein gankyrin binds to MDM2/HDM2, enhancing ubiquitylation and degradation of p53. | None |
| MDM2 can interact with the C-terminus of AID but it is inessential for antibody diversification in DT40 B cells. | None |
| Genistein, a dietary isoflavone, down-regulates the MDM2 oncogene at both transcriptional and posttranslational levels. | None |
| Characterisation of a novel p53 down-regulated promoter in intron 3 of the human MDM2 oncogene. | None |
| Oscillations and variability in the p53 system. | None |
| Intrinsic ubiquitination activity of PCAF controls the stability of the oncoprotein Hdm2. | None |
| Curcumin, a dietary component, has anticancer, chemosensitization, and radiosensitization effects by down-regulating the MDM2 oncogene through the PI3K/mTOR/ETS2 pathway. | None |
| Haplotype structure and selection of the MDM2 oncogene in humans. | None |
| analysis of haplotype structure and selection of the MDM2 oncogene in humans | None |
| This is an overview/review of the p53-proto-oncogene protein MDM2 module and its associated pathways from a systems biology perspective. In normal cells, MDM2 negatively regulates the activity of p53. | None |
| The p53-MDM2 network: from oscillations to apoptosis. | None |
| stabilization of MDMX by Akt may be an alternative mechanism by which Akt up-regulates MDM2 protein levels and exerts its oncogenic effects on p53 in tumor cells | None |
| NFBD1/MDC1 stabilizes oncogenic MDM2 to contribute to cell fate determination in response to DNA damage. | None |
| MUC1 oncoprotein suppresses activation of the ARF-MDM2-p53 pathway. | None |
| Hdm2 protein is a ku autoantigen ibiquitin ligase and that Proto-Oncogene Proteins c-akt inhibits Bax-mediated apoptosis by maintaining Ku autoantigen levels through the promotion of Hdm2 protein nuclear translocation. | None |
| Gambogic acid down-regulates MDM2 oncogene and induces p21(Waf1/CIP1) expression independent of p53. | None |
| Jmjd2c histone demethylase enhances the expression of Mdm2 oncogene. | None |
| These results indicate that Mdm2 oncogene is a downstream target of Jmjd2c and may play an important role in Jmjd2c-mediated oncogenesis. | None |
| p53 Promotes proteasome-dependent degradation of oncogenic protein HBx by transcription of MDM2. | None |