Sentence and cancer type
Showing 121-140 of 180 items.
SentenceCancertype
The Mdm2-p53 relationship evolves: Mdm2 swings both ways as an oncogene and a tumor suppressor. None
Phosphorylation by casein kinase I promotes the turnover of the Mdm2 oncoprotein via the SCF(beta-TRCP) ubiquitin ligase. None
A novel oncoprotein Pirh2: rising from the shadow of MDM2. None
Human oncoprotein mdm2 interacts with the tata-binding protein in-vitro and in-vivo. None
The in vivo role of the RP-Mdm2-p53 pathway in signaling oncogenic stress induced by pRb inactivation and Ras overexpression. None
Recombinant human MDM2 oncoprotein shows sequence composition selectivity for binding to both RNA and DNA. None
Mdm2 associates with Ras effector NORE1 to induce the degradation of oncoprotein HIPK1. None
Overexpression of SKI oncoprotein leads to p53 degradation through regulation of MDM2 protein sumoylation. None
HPV-16 E6 and E7 oncogene expression is downregulated as a result of Mdm2 knockdown. None
Transcription factor NFAT1 activates the mdm2 oncogene independent of p53.None
Transcription factor NFAT1 activates the mdm2 oncogene independent of p53. None
Human oncoprotein MDM2 activates the Akt signaling pathway through an interaction with the repressor element-1 silencing transcription factor conferring a survival advantage to cancer cells. None
FEZF2 acted as a histone deacetylase-associated repressor downregulating multiple oncogenes including EZH2 and MDM2, through direct binding to their promoters.None
The human oncoprotein MDM2 induces replication stress eliciting early intra-S-phase checkpoint response and inhibition of DNA replication origin firing. None
Novel perspective: exercise training stimulus triggers the expression of the oncoprotein human double minute-2 in human skeletal muscle. None
The regulation of MDM2 oncogene and its impact on human cancers. None
Data show that NEDD4-1 E3 ligase as a novel component of the tumor suppressor protein p53/proto-oncogene proteins c-mdm2 regulatory feedback loop that controls p53 activity during stress responses.None
Regulation of Mdm2 protein stability and the p53 response by NEDD4-1 E3 ligase. None
Polymorphism of P53-Ets/AP1 transactivation region of MDM2 oncogene and its immunohistochemical analysis in canine tumours. None
results reveal a novel p53- and Mdm2-independent oncogenic function of Mdmx that provides new insight into the many cancers that overexpress Mdmx.None