| Altered tumor formation and evolutionary selection of genetic variants in the human MDM4 oncogene. | None |
| HDMX exhibits bona fide oncogenic properties | None |
| Mdm4 is thus a bona fide oncogene in vivo and cooperates with p53 heterozygosity to drive tumorigenesis. | None |
| Our studies show that hMDMX has the essential properties of an oncogene | None |
| results reveal a novel p53- and Mdm2-independent oncogenic function of Mdmx that provides new insight into the many cancers that overexpress Mdmx. | None |
| MDMX exerts oncogenic activity via suppression of RB. | None |